Observations on Semantic Annotation of Microscope Images for Life Sciences
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چکیده
Microscopy images are important in the Life Sciences. These images not only vary in scale but also in modality, making it hard to do image registration. Ontology annotation helps us to link the images, but not all researchers in the Life Sciences are familiar with ontologies. The Cyttron Scientific Image Database for Exchange (CSIDx) presents different tools to help users annotate their images. When taking microscopy techniques and methods into account, one cannot correlate images from the Life Sciences domain on a pixel by pixel basis. Even images with the same subject matter change so drastically with modality that it becomes impossible for classical image retrieval techniques to deal with this particular domain. The resulting images range from one-dimensional to more than four-dimensional artifacts. Without any added information it is impossible to discern the nature of these images. Semantic relations are needed to make the connections between the images. An important part of the semantics is not only the subject matter but also the modality of the image. A good collection of ontologies can be found in the OBO Foundry. This consortium curates ontologies geared towards the Life Sciences and also provides mappings between different ontologies. Concepts from ontologies can be used to enrich images by associating each image with multiple ontology concepts. These concepts can come from many multiple ontologies. This allows maximum freedom for the user to annotate their images, while restricting them to a controlled vocabulary.
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تاریخ انتشار 2009